| Peak Inspiratory Pressure Thresholds | Complications |
|---|---|
| 20 cmH2o | Lower esophageal sphincter (LES) opening pressure. 1,2 |
| Gastric insufflation occurs. 3 | |
| 30 cmH2o | Onset of lung injury 4,5 |
| 40 cmH20 | Barotrauma, interstitial edema, and inflammation 6 |
| 57-62 cmH20 | Pneumomediastinum and pneumothorax 7 |
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